Chimerism after organ transplantation

Chimerism after organ transplantation.

Recent evidence suggests that passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allograft. Here, we describe how this hematolymphopoietic chimerism provides an important framework for interpretation of post-transplant phenomena and for initiation of therapeutically oriented transplantation research.

Chimerism After Whole Organ Transplantation :

Chimerism after Whole Organ Transplant.

Chimerism and Tolerance in Solid Organ Transplantation

J Clin Cell Immunol ISSN:2155-9899 JCCI, an open access journal Transplantation Immunology *Corresponding authors: Suzanne T. Ildstad, M.D., Director, Institute for Cellular Therapeutics, Jewish Hospital, Distinguished Professor of Transplantation, Distinguished University Scholar, Professor of Surgery, University of Louisville, 570 South Preston Street, Suite 404, Louisville, Kentucky 40202-17...

Xenobiotics, chimerism and the induction of tolerance following organ transplantation.

The successful results seen after organ transplantation are largely attributable to the potency and specificity of modern immunosuppressive agents. Although drug-free unresponsiveness to graft alloantigens has not been routinely achieved in clinical practice, recent appreciation of the importance of cell chimerism, which develops after the migration from donor to host of leukocytes contained in...